Abstract
Ruthenium(ii) tris(bipyridyl) protein surface mimetics are used in an array format to sense and discriminate proteins including therapeutically relevant targets, hDM2 and MCL-1, using linear discriminant analysis (LDA).
| Original language | English |
|---|---|
| Pages (from-to) | 12278-12281 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 53 |
| Issue number | 91 |
| DOIs | |
| Publication status | Published - 2017 |
Bibliographical note
Funding Information:This work was supported by the Engineering and Physical Sciences Research Council [EP/L504993/1, EP/F039069, EP/F038712 and EP/N013573/1]. We would like to thank Kat Horner for synthesis of the NOXA-B peptide, Kirstin Spence for expression of hDM2 and MCL-1 and Georgina Pleasance for initial synthesis of complex 4.
Publisher Copyright:
© 2017 The Royal Society of Chemistry.
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
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