Progressive supranuclear palsy.

K Tawana, David Ramsden

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

This review concentrates on the molecular pathology of the protein tau, including its expression in various regions of the brain. The role of post-translational modifications in fibrillogenesis is also discussed, particularly hyperphosphorylation and glycation. However, the initiating event that causes aberrant tau processing remains unclear.
Original languageEnglish
Pages (from-to)427-34
Number of pages8
JournalMolecular Pathology
Volume54
Issue number6
Publication statusPublished - 1 Dec 2001

Keywords

  • neurodegenerative disease
  • progressive supranuclear palsy
  • tau protein filaments
  • oxidative stress

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