Primary hyperparathyroidism--is mild disease worth treating?

Neil Gittoes, Mark Cooper

Research output: Contribution to journalReview article

7 Citations (Scopus)


Most patients with primary hyperparathyroidism (PHPT) are asymptomatic at presentation. This presents the dilemma whether to treat surgically or manage by conservative follow-up. This article covers the risks of managing mild PHPT conservatively. Some of these risks are well established, for example worsening of bone disease and increased risk of nephrolithiasis. Others, such as effects on cardiovascular function or the risk of malignancy are more controversial. These factors are critical to decisions relating to surgical or conservative management of mild PHPT.
Original languageEnglish
Pages (from-to)45-9
Number of pages5
JournalClinical Medicine
Issue number1
Publication statusPublished - 1 Feb 2010


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