Prevalence of vitamin D deficiency and modifiable risk factors in patients with Crohn's disease: A prospective observational study

Jane Fletcher*, Michaela Brown, Martin Hewison, Amelia Swift, Sheldon C. Cooper

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Aims
To determine the prevalence of vitamin D deficiency in adults with Crohn's Disease (CD) in Birmingham, UK (latitude 52.4°N, −1.9°E) and identify modifiable risk factors.

Design/Method
A nurse-led, single-centre, prospective study was conducted over 5 months in 2019 and 2020 in outpatients with CD, at a tertiary referral hospital in Birmingham UK. Vitamin D (25OHD) levels were measured at a single timepoint by a dried blood spot sample. Modifiable risk factor data were collected including intake of vitamin D-containing foods, use of vitamin D supplements, sun exposure and current smoking.

Results
Total 150 participants (53.3% male, 79.3% white British). Vitamin D deficiency (25OHD
Conclusion
Patients with CD are at high risk of vitamin D deficiency as defined by 25OHD 
Impact
Patients with Crohn's Disease are at high risk of developing vitamin D deficiency but there is little data from the UK at this latitude.
We demonstrate the prevalence and severity of vitamin D deficiency in people with Crohn's Disease in the UK.
The prevalence of vitamin D deficiency in this group is high and warrants monitoring by nurses and clinical teams. Nurses and clinical teams should consider strategies for vitamin D supplementation in patients with Crohn's Disease.
Original languageEnglish
Pages (from-to)205-214
JournalJournal of Advanced Nursing
Volume79
Issue number1
Early online date24 Oct 2022
DOIs
Publication statusPublished - Jan 2023

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