Practical guidance for running late-phase platform protocols for clinical trials: lessons from experienced UK clinical trials units

Sharon B Love, Fay Cafferty, Claire Snowdon, Karen Carty, J Savage, P Pallmann, L McParland, Louise J Brown, Lindsey Masters, Francesca Schiavone, Dominic Hague, Stephen Townsend, Claire Amos, Annabelle South, Kate Sturgeon, Ruth E Langley, Timothy S Maughan, Nicholas James, Emma Hall, Sarah KernaghanJudith Bliss, Nicholas C. Turner, Christina Yap, Charlotte Firth, Anthony Kong, Hisham Mehanna, Colin Watts, Robert Hills, Ian Thomas, Mhairi Copland, Sue E Bell, Andrew N J Tutt, David Sebag-Montefiore, Robert Jones, Mahesh K B Parmar, Matthew R Sydes

Research output: Working paper/PreprintPreprint

Original languageEnglish
PublisherResearch Square
DOIs
Publication statusPublished - 9 Mar 2022

Keywords

  • Platform protocols
  • Trial conduct
  • Multi-arm multi-stage trials
  • Umbrella trials
  • Basket trials
  • Stratified medicine
  • Complex innovative designs
  • Methodology

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