Porcine dermal matrix in the treatment of dehiscence-type defects--an experimental split-mouth animal trial

Stefan Fickl; Ulf Nannmark; Ulrich Schlagenhauf; Markus B Hürzeler; Moritz Kebschull

doi:10.1111/clr.12355

Porcine dermal matrix in the treatment of dehiscence-type defects--an experimental split-mouth animal trial

Stefan Fickl, Ulf Nannmark, Ulrich Schlagenhauf, Markus B Hürzeler, Moritz Kebschull

Dentistry

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

OBJECTIVES: To describe histometrical outcomes (tissue thickness, tissue height) of a porcine dermal matrix (PDX) and subepithelial connective tissue (CTG) in the treatment of dehiscence-type defects.

MATERIAL AND METHODS: In five beagle dogs buccal dehiscence defects were created on both upper canines. The defects were covered in a split-mouth design either with a porcine dermal matrix or subepithelial connective tissue. After 4 months histometrical outcomes were evaluated using a nonparametric Brunner-Langer model.

RESULTS: Neither in the test nor in the control specimen signs of inflammation or foreign body reaction was detected. Histometrically, no significant difference was found for tissue thickness and height between both treatment groups.

CONCLUSIONS: Porcine dermal matrix can be used for grafting of dehiscence-type defects. Augmentation of tissue thickness seems to be comparable to subepithelial connective tissue.

Original language	English
Pages (from-to)	799-805
Number of pages	7
Journal	Clinical Oral Implants Research
Volume	26
Issue number	7
Early online date	19 Feb 2014
DOIs	https://doi.org/10.1111/clr.12355
Publication status	Published - Jul 2015

Keywords

Acellular Dermis
Animals
Biopsy
Connective Tissue/transplantation
Dogs
Gingival Recession/surgery
Gingivoplasty/methods
Random Allocation
Surgical Flaps
Suture Techniques
Swine

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https://onlinelibrary.wiley.com/doi/full/10.1111/clr.12355Licence: None: All rights reserved

Cite this

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title = "Porcine dermal matrix in the treatment of dehiscence-type defects--an experimental split-mouth animal trial",

abstract = "OBJECTIVES: To describe histometrical outcomes (tissue thickness, tissue height) of a porcine dermal matrix (PDX) and subepithelial connective tissue (CTG) in the treatment of dehiscence-type defects.MATERIAL AND METHODS: In five beagle dogs buccal dehiscence defects were created on both upper canines. The defects were covered in a split-mouth design either with a porcine dermal matrix or subepithelial connective tissue. After 4 months histometrical outcomes were evaluated using a nonparametric Brunner-Langer model.RESULTS: Neither in the test nor in the control specimen signs of inflammation or foreign body reaction was detected. Histometrically, no significant difference was found for tissue thickness and height between both treatment groups.CONCLUSIONS: Porcine dermal matrix can be used for grafting of dehiscence-type defects. Augmentation of tissue thickness seems to be comparable to subepithelial connective tissue.",

keywords = "Acellular Dermis, Animals, Biopsy, Connective Tissue/transplantation, Dogs, Gingival Recession/surgery, Gingivoplasty/methods, Random Allocation, Surgical Flaps, Suture Techniques, Swine",

author = "Stefan Fickl and Ulf Nannmark and Ulrich Schlagenhauf and H{\"u}rzeler, {Markus B} and Moritz Kebschull",

note = "{\textcopyright} 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",

year = "2015",

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doi = "10.1111/clr.12355",

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T1 - Porcine dermal matrix in the treatment of dehiscence-type defects--an experimental split-mouth animal trial

AU - Fickl, Stefan

AU - Nannmark, Ulf

AU - Schlagenhauf, Ulrich

AU - Hürzeler, Markus B

AU - Kebschull, Moritz

PY - 2015/7

Y1 - 2015/7

N2 - OBJECTIVES: To describe histometrical outcomes (tissue thickness, tissue height) of a porcine dermal matrix (PDX) and subepithelial connective tissue (CTG) in the treatment of dehiscence-type defects.MATERIAL AND METHODS: In five beagle dogs buccal dehiscence defects were created on both upper canines. The defects were covered in a split-mouth design either with a porcine dermal matrix or subepithelial connective tissue. After 4 months histometrical outcomes were evaluated using a nonparametric Brunner-Langer model.RESULTS: Neither in the test nor in the control specimen signs of inflammation or foreign body reaction was detected. Histometrically, no significant difference was found for tissue thickness and height between both treatment groups.CONCLUSIONS: Porcine dermal matrix can be used for grafting of dehiscence-type defects. Augmentation of tissue thickness seems to be comparable to subepithelial connective tissue.

AB - OBJECTIVES: To describe histometrical outcomes (tissue thickness, tissue height) of a porcine dermal matrix (PDX) and subepithelial connective tissue (CTG) in the treatment of dehiscence-type defects.MATERIAL AND METHODS: In five beagle dogs buccal dehiscence defects were created on both upper canines. The defects were covered in a split-mouth design either with a porcine dermal matrix or subepithelial connective tissue. After 4 months histometrical outcomes were evaluated using a nonparametric Brunner-Langer model.RESULTS: Neither in the test nor in the control specimen signs of inflammation or foreign body reaction was detected. Histometrically, no significant difference was found for tissue thickness and height between both treatment groups.CONCLUSIONS: Porcine dermal matrix can be used for grafting of dehiscence-type defects. Augmentation of tissue thickness seems to be comparable to subepithelial connective tissue.

KW - Acellular Dermis

KW - Animals

KW - Biopsy

KW - Connective Tissue/transplantation

KW - Dogs

KW - Gingival Recession/surgery

KW - Gingivoplasty/methods

KW - Random Allocation

KW - Surgical Flaps

KW - Suture Techniques

KW - Swine

U2 - 10.1111/clr.12355

DO - 10.1111/clr.12355

M3 - Article

C2 - 24547948

SN - 0905-7161

VL - 26

SP - 799

EP - 805

JO - Clinical Oral Implants Research

JF - Clinical Oral Implants Research

IS - 7

ER -

Porcine dermal matrix in the treatment of dehiscence-type defects--an experimental split-mouth animal trial

Abstract

Keywords

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