Pneumococcus adapts to the sickle cell host

Tim J Mitchell; Andrea M Mitchell

doi:10.1016/j.chom.2014.04.013

Pneumococcus adapts to the sickle cell host

Tim J Mitchell, Andrea M Mitchell

Microbiology and Infection

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Abstract

Children with sickle cell disease (SCD) have significantly increased risk of invasive pneumococcal disease. In this issue of Cell Host & Microbe, Carter et al. (2014) report that pneumococcal strains from SCD children have genetic mutations associated with the unique SCD environment, which need to be considered in developing new vaccines.

Original language	English
Pages (from-to)	521-523
Number of pages	3
Journal	Cell Host & Microbe
Volume	15
Issue number	5
DOIs	https://doi.org/10.1016/j.chom.2014.04.013
Publication status	Published - 14 May 2014

Bibliographical note

Keywords

Anemia, Sickle Cell
Bacterial Proteins
Female
Host-Pathogen Interactions
Humans
Male
Pneumococcal Infections
Streptococcus pneumoniae

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

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title = "Pneumococcus adapts to the sickle cell host",

abstract = "Children with sickle cell disease (SCD) have significantly increased risk of invasive pneumococcal disease. In this issue of Cell Host & Microbe, Carter et al. (2014) report that pneumococcal strains from SCD children have genetic mutations associated with the unique SCD environment, which need to be considered in developing new vaccines.",

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AU - Mitchell, Tim J

AU - Mitchell, Andrea M

PY - 2014/5/14

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AB - Children with sickle cell disease (SCD) have significantly increased risk of invasive pneumococcal disease. In this issue of Cell Host & Microbe, Carter et al. (2014) report that pneumococcal strains from SCD children have genetic mutations associated with the unique SCD environment, which need to be considered in developing new vaccines.

KW - Anemia, Sickle Cell

KW - Bacterial Proteins

KW - Female

KW - Host-Pathogen Interactions

KW - Humans

KW - Male

KW - Pneumococcal Infections

KW - Streptococcus pneumoniae

U2 - 10.1016/j.chom.2014.04.013

DO - 10.1016/j.chom.2014.04.013

M3 - Article

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SN - 1931-3128

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EP - 523

JO - Cell Host & Microbe

JF - Cell Host & Microbe

IS - 5

ER -

Pneumococcus adapts to the sickle cell host

Abstract

Bibliographical note

Keywords

UN SDGs

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