Plasma haemoxygenase-1 in coronary artery disease A comparison with angiogenin, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 and vascular endothelial growth factor

NK Idriss; Gregory Lip; B Balakrishnan; Rumi Jaumdally; Christopher Boos; Andrew Blann

doi:10.1160/TH09.11.0802

Plasma haemoxygenase-1 in coronary artery disease A comparison with angiogenin, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 and vascular endothelial growth factor

NK Idriss, Gregory Lip, B Balakrishnan, Rumi Jaumdally, Christopher Boos, Andrew Blann

Research output: Contribution to journal › Article

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Abstract

It was the aim of this study to determine plasma haemoxygenase 1 (HO 1) across the spectrum of health, angina but normal coronary arteries (NCA) stable coronary artery disease (CAD) and acute coronary syndromes (ACS) and relationships with angiogenin matrix metallo proteinase 9 (MMP 9), tissue inhibitor of metalloproteinase 1, and vascular endothelial growth factor Plasma markers were measured (ELISA) in peripheral venous citrated plasma from 50 healthy subjects 30 with NCA, 70 with stable CAD and 24 with an ACS and from patient s aortic root coronary ostium coronary sinus and femoral artery Human umbilical vein endothelial cells (HUVECs) were cultured with or without tumour necrosis factor (TNF) and platelets were probed HO 1 was raised in stable CAD (p

Original language	English
Pages (from-to)	1029-1037
Number of pages	9
Journal	Thrombosis and Haemostasis
Volume	104
Issue number	5
DOIs	https://doi.org/10.1160/TH09.11.0802
Publication status	Published - 1 Nov 2010

Keywords

coronary artery disease
vascular endothelial growth factor
tissue inhibitor of metalloproteinase
Haemoxygenase 1 angiogenin matrix metalloproteinase 9

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1160/TH09.11.0802

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abstract = "It was the aim of this study to determine plasma haemoxygenase 1 (HO 1) across the spectrum of health, angina but normal coronary arteries (NCA) stable coronary artery disease (CAD) and acute coronary syndromes (ACS) and relationships with angiogenin matrix metallo proteinase 9 (MMP 9), tissue inhibitor of metalloproteinase 1, and vascular endothelial growth factor Plasma markers were measured (ELISA) in peripheral venous citrated plasma from 50 healthy subjects 30 with NCA, 70 with stable CAD and 24 with an ACS and from patient s aortic root coronary ostium coronary sinus and femoral artery Human umbilical vein endothelial cells (HUVECs) were cultured with or without tumour necrosis factor (TNF) and platelets were probed HO 1 was raised in stable CAD (p",

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doi = "10.1160/TH09.11.0802",

language = "English",

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T1 - Plasma haemoxygenase-1 in coronary artery disease A comparison with angiogenin, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 and vascular endothelial growth factor

AU - Idriss, NK

AU - Lip, Gregory

AU - Balakrishnan, B

AU - Jaumdally, Rumi

AU - Boos, Christopher

AU - Blann, Andrew

PY - 2010/11/1

Y1 - 2010/11/1

N2 - It was the aim of this study to determine plasma haemoxygenase 1 (HO 1) across the spectrum of health, angina but normal coronary arteries (NCA) stable coronary artery disease (CAD) and acute coronary syndromes (ACS) and relationships with angiogenin matrix metallo proteinase 9 (MMP 9), tissue inhibitor of metalloproteinase 1, and vascular endothelial growth factor Plasma markers were measured (ELISA) in peripheral venous citrated plasma from 50 healthy subjects 30 with NCA, 70 with stable CAD and 24 with an ACS and from patient s aortic root coronary ostium coronary sinus and femoral artery Human umbilical vein endothelial cells (HUVECs) were cultured with or without tumour necrosis factor (TNF) and platelets were probed HO 1 was raised in stable CAD (p

AB - It was the aim of this study to determine plasma haemoxygenase 1 (HO 1) across the spectrum of health, angina but normal coronary arteries (NCA) stable coronary artery disease (CAD) and acute coronary syndromes (ACS) and relationships with angiogenin matrix metallo proteinase 9 (MMP 9), tissue inhibitor of metalloproteinase 1, and vascular endothelial growth factor Plasma markers were measured (ELISA) in peripheral venous citrated plasma from 50 healthy subjects 30 with NCA, 70 with stable CAD and 24 with an ACS and from patient s aortic root coronary ostium coronary sinus and femoral artery Human umbilical vein endothelial cells (HUVECs) were cultured with or without tumour necrosis factor (TNF) and platelets were probed HO 1 was raised in stable CAD (p

KW - coronary artery disease

KW - vascular endothelial growth factor

KW - tissue inhibitor of metalloproteinase

KW - Haemoxygenase 1 angiogenin matrix metalloproteinase 9

U2 - 10.1160/TH09.11.0802

DO - 10.1160/TH09.11.0802

M3 - Article

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EP - 1037

JO - Thrombosis and Haemostasis

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IS - 5

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Plasma haemoxygenase-1 in coronary artery disease A comparison with angiogenin, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 and vascular endothelial growth factor

Abstract

Keywords

UN SDGs

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