Photonic hydrogel sensors

Ali K Yetisen, Haider Butt, Lisa R Volpatti, Ida Pavlichenko, Matjaž Humar, Sheldon J J Kwok, Heebeom Koo, Ki Su Kim, Izabela Naydenova, Ali Khademhosseini, Sei Kwang Hahn, Seok Hyun Yun

Research output: Contribution to journalArticlepeer-review

92 Citations (Scopus)
434 Downloads (Pure)

Abstract

Analyte-sensitive hydrogels that incorporate optical structures have emerged as sensing platforms for point-of-care diagnostics. The optical properties of the hydrogel sensors can be rationally designed and fabricated through self-assembly, microfabrication or laser writing. The advantages of photonic hydrogel sensors over conventional assay formats include label-free, quantitative, reusable, and continuous measurement capability that can be integrated with equipment-free text or image display. This review explains the operation principles of photonic hydrogel sensors, presents syntheses of stimuli-responsive polymers, and provides an overview of qualitative and quantitative readout technologies. Applications in clinical samples are discussed, and potential future directions are identified.

Original languageEnglish
JournalBiotechnology Advances
Early online date17 Oct 2015
DOIs
Publication statusE-pub ahead of print - 17 Oct 2015

Bibliographical note

Copyright © 2015. Published by Elsevier Inc.

Keywords

  • Hydrogels
  • In vitro diagnostics
  • Photonic crystals
  • Inverse opals
  • Holography
  • Bragg stacks
  • Crystalline colloidal arrays
  • Block copolymers
  • Layer-by-layer deposition
  • Plasmonics

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