Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA

Jack Manchester; Dario M Bassani; Jean-Louis H A Duprey; Luciana Giordano; Joseph S Vyle; Zheng-yun Zhao; James H R Tucker

doi:10.1021/ja304205m

Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA

Jack Manchester
, Dario M Bassani
, Jean-Louis H A Duprey
, Luciana Giordano
, Joseph S Vyle
, Zheng-yun Zhao
, James H R Tucker

Chemistry

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.

Original language	English
Pages (from-to)	10791-4
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	134
Issue number	26
DOIs	https://doi.org/10.1021/ja304205m
Publication status	Published - 2012

Access to Document

10.1021/ja304205m

Functional DNA-based assemblies
Tucker, J. (Principal Investigator)
Engineering & Physical Science Research Council
16/03/09 → 31/03/14
Project: Research Councils
Controlling the Molecular Motion Associated with Pyramidal Inversion : Towards New Types of Nanoscale Switches
Tucker, J. (Principal Investigator)
Engineering & Physical Science Research Council
1/04/08 → 31/12/10
Project: Research Councils

Cite this

@article{8d69ea5657824826ad6991bdd2775a76,

title = "Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA",

abstract = "Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.",

author = "Jack Manchester and Bassani, \{Dario M\} and Duprey, \{Jean-Louis H A\} and Luciana Giordano and Vyle, \{Joseph S\} and Zheng-yun Zhao and Tucker, \{James H R\}",

year = "2012",

doi = "10.1021/ja304205m",

language = "English",

volume = "134",

pages = "10791--4",

journal = "Journal of the American Chemical Society",

issn = "1520-5126",

publisher = "American Chemical Society",

number = "26",

}

TY - JOUR

T1 - Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA

AU - Manchester, Jack

AU - Bassani, Dario M

AU - Duprey, Jean-Louis H A

AU - Giordano, Luciana

AU - Vyle, Joseph S

AU - Zhao, Zheng-yun

AU - Tucker, James H R

PY - 2012

Y1 - 2012

N2 - Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.

AB - Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.

U2 - 10.1021/ja304205m

DO - 10.1021/ja304205m

M3 - Article

C2 - 22694485

SN - 1520-5126

VL - 134

SP - 10791

EP - 10794

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 26

ER -

Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA

Abstract

Access to Document

Fingerprint

Projects

Functional DNA-based assemblies

Controlling the Molecular Motion Associated with Pyramidal Inversion : Towards New Types of Nanoscale Switches

Cite this