PHENYL CARBAMATES AND THEIR USE AS INHIBITORS OF THE FATTY ACID AMIDE HYDROLASE (FAAH) ENZYME AND MODULATORS OF THE D3 DOPAMINE RECEPTOR (D3DR)

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (Inventor), THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Inventor), Giovanni BOTTEGONI (Inventor), Alessio DE SIMONE (Inventor), Gian Filippo RUDA (Inventor), Andrea CAVALLI (Inventor), Tiziano BANDIERA (Inventor), Daniele PIOMELLI (Inventor)

Research output: Patent

Abstract

The invention provides compounds of Formula (I) or pharmaceutically acceptable salts thereof wherein Ar', R1, R2, R3, R4, X, Y are as defined in the description of invention, as multi-target directed ligands (MTDLs) that are at the same time inhibitors of the fatty acid amide hydrolase (FAAH) enzyme and modulators of the D3 dopamine receptor (D3DR), their methods of preparation, formulations and therapeutic applications thereof.
Original languageEnglish
Patent numberWO2015/7615
Publication statusPublished - 2015

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