Abstract
The present study determined the detailed pharmacological profile of heterologously expressed human (h) homomeric 5-HT3A receptors in direct comparison to heteromeric h5-HT3A/3B receptors. The very minor differences in their respective pharmacological profiles indicates that the 5-HT3B receptor subunit alters, predominantly, the biophysical rather than the pharmacological properties of the 5-HT3 receptor. (C) 2001 Elsevier Science Ltd. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 282-284 |
| Number of pages | 3 |
| Journal | Neuropharmacology |
| Volume | 41 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1 Aug 2001 |
Keywords
- 5-HT3 receptor
- 5-HT3B subunit
- ligand-gated ion channel
- 5-HT3A subunit
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