Pattern of atrial fibrillation and risk of outcomes: The Loire Valley Atrial Fibrillation Project

Amitava Banerjee; Sophie Taillandier; Jonas Bjerring Olesen; Deirdre A Lane; Benedicte Lallemand; Gregory Y H Lip; Laurent Fauchier

doi:10.1016/j.ijcard.2012.06.118

Pattern of atrial fibrillation and risk of outcomes: The Loire Valley Atrial Fibrillation Project

Amitava Banerjee
, Sophie Taillandier
, Jonas Bjerring Olesen
, Deirdre A Lane
, Benedicte Lallemand
, Gregory Y H Lip
, Laurent Fauchier

Cardiovascular Sciences

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

Abstract

BACKGROUND: Risk of stroke and thromboembolism (TE) in patients with non-valvular atrial fibrillation (NVAF) is categorised in stroke risk stratification scores. The role of pattern of NVAF in risk prediction is unclear in contemporary 'real world' cohorts. METHODS AND RESULTS: Patients with NVAF in a four-hospital-institution between 2000 and 2010 were included. Stroke/TE event rates were calculated according to pattern of AF, i.e. paroxysmal, persistent and permanent. Risk factors were investigated by Cox regression. Among 7156 NVAF patients, 4176 (58.4%) patients with paroxysmal, 376 (5.3%) with persistent and 2604 (36.3%) with permanent patterns of NVAF were included. In non-anticoagulated patients, overall stroke/TE event rate per 100 person-years was 1.29 (95% CI 1.13-1.47). Compared with paroxysmal NVAF, rates of stroke/TE, bleeding and all-cause mortality (p

Original language	English
Journal	International Journal of Cardiology
DOIs	https://doi.org/10.1016/j.ijcard.2012.06.118
Publication status	Published - 2012

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10.1016/j.ijcard.2012.06.118

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title = "Pattern of atrial fibrillation and risk of outcomes: The Loire Valley Atrial Fibrillation Project",

abstract = "BACKGROUND: Risk of stroke and thromboembolism (TE) in patients with non-valvular atrial fibrillation (NVAF) is categorised in stroke risk stratification scores. The role of pattern of NVAF in risk prediction is unclear in contemporary 'real world' cohorts. METHODS AND RESULTS: Patients with NVAF in a four-hospital-institution between 2000 and 2010 were included. Stroke/TE event rates were calculated according to pattern of AF, i.e. paroxysmal, persistent and permanent. Risk factors were investigated by Cox regression. Among 7156 NVAF patients, 4176 (58.4\%) patients with paroxysmal, 376 (5.3\%) with persistent and 2604 (36.3\%) with permanent patterns of NVAF were included. In non-anticoagulated patients, overall stroke/TE event rate per 100 person-years was 1.29 (95\% CI 1.13-1.47). Compared with paroxysmal NVAF, rates of stroke/TE, bleeding and all-cause mortality (p",

author = "Amitava Banerjee and Sophie Taillandier and Olesen, \{Jonas Bjerring\} and Lane, \{Deirdre A\} and Benedicte Lallemand and Lip, \{Gregory Y H\} and Laurent Fauchier",

year = "2012",

doi = "10.1016/j.ijcard.2012.06.118",

language = "English",

journal = "International Journal of Cardiology",

publisher = "Elsevier",

}

TY - JOUR

T1 - Pattern of atrial fibrillation and risk of outcomes

T2 - The Loire Valley Atrial Fibrillation Project

AU - Banerjee, Amitava

AU - Taillandier, Sophie

AU - Olesen, Jonas Bjerring

AU - Lane, Deirdre A

AU - Lallemand, Benedicte

AU - Lip, Gregory Y H

AU - Fauchier, Laurent

PY - 2012

Y1 - 2012

N2 - BACKGROUND: Risk of stroke and thromboembolism (TE) in patients with non-valvular atrial fibrillation (NVAF) is categorised in stroke risk stratification scores. The role of pattern of NVAF in risk prediction is unclear in contemporary 'real world' cohorts. METHODS AND RESULTS: Patients with NVAF in a four-hospital-institution between 2000 and 2010 were included. Stroke/TE event rates were calculated according to pattern of AF, i.e. paroxysmal, persistent and permanent. Risk factors were investigated by Cox regression. Among 7156 NVAF patients, 4176 (58.4%) patients with paroxysmal, 376 (5.3%) with persistent and 2604 (36.3%) with permanent patterns of NVAF were included. In non-anticoagulated patients, overall stroke/TE event rate per 100 person-years was 1.29 (95% CI 1.13-1.47). Compared with paroxysmal NVAF, rates of stroke/TE, bleeding and all-cause mortality (p

AB - BACKGROUND: Risk of stroke and thromboembolism (TE) in patients with non-valvular atrial fibrillation (NVAF) is categorised in stroke risk stratification scores. The role of pattern of NVAF in risk prediction is unclear in contemporary 'real world' cohorts. METHODS AND RESULTS: Patients with NVAF in a four-hospital-institution between 2000 and 2010 were included. Stroke/TE event rates were calculated according to pattern of AF, i.e. paroxysmal, persistent and permanent. Risk factors were investigated by Cox regression. Among 7156 NVAF patients, 4176 (58.4%) patients with paroxysmal, 376 (5.3%) with persistent and 2604 (36.3%) with permanent patterns of NVAF were included. In non-anticoagulated patients, overall stroke/TE event rate per 100 person-years was 1.29 (95% CI 1.13-1.47). Compared with paroxysmal NVAF, rates of stroke/TE, bleeding and all-cause mortality (p

U2 - 10.1016/j.ijcard.2012.06.118

DO - 10.1016/j.ijcard.2012.06.118

M3 - Article

C2 - 22795403

JO - International Journal of Cardiology

JF - International Journal of Cardiology

ER -

Pattern of atrial fibrillation and risk of outcomes: The Loire Valley Atrial Fibrillation Project

Abstract

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