Pathways of mammalian replication fork restart

Research output

Research output per year 2009 2009 2010 2010

• 265 Citations
• 2 Article

Research output per year

Research output per year

Search results

• 2010

  Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

  Petermann, E., Orta, ML., Issaeva, N., Schultz, N. & Helleday, T., 1 Feb 2010, In: Molecular Cell. 37, 4, p. 492-502 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydroxyurea 100%
  • Homologous Recombination 92%
  • X-ray repair cross complementing protein 3 82%
  • 1,2-di-(4-sulfamidophenyl)-4-butylpyrazolidine-3,5-dione 60%
  • Recombinational DNA Repair 53%
  493 Citations (Scopus)

  4 Downloads (Pure)
• 2009

  PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination

  Bryant, HE., Petermann, E., Schultz, N., Jemth, AS., Loseva, O., Issaeva, N., Johansson, F., Fernandez, S., McGlynn, P. & Helleday, T., 2 Sept 2009, In: The EMBO journal. 28, 17, p. 2601-2615 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Poly (ADP-Ribose) Polymerase-1 100%
  • Poly(ADPribose) 99%
  • Genetic Recombination 69%
  • Block Like Crystal 24%
  • Recombinational DNA Repair 23%
  392 Citations (Scopus)

  8 Downloads (Pure)