Parental Death during Childhood and Adult Cardiovascular Risk in a Developing Country: The Guangzhou Biobank Cohort Study

CM Schooling; C Jiang; TH Lam; W Zhang; Kar Cheng; GM Leung

doi:10.1371/journal.pone.0019675

Parental Death during Childhood and Adult Cardiovascular Risk in a Developing Country: The Guangzhou Biobank Cohort Study

CM Schooling, C Jiang, TH Lam, W Zhang, Kar Cheng, GM Leung

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Abstract

Background: In observational studies from western countries childhood emotional adversity is usually associated with adult cardiovascular disease. These findings are open to contextual biases making evidence from other settings valuable. We examined the association of a potential marker of childhood emotional adversity with cardiovascular disease risk factors in a developing country. Methods: We used multivariable regression in cross-sectional analysis of older (>= 50 years) men (n = 7,885) and women (n = 20,886) from the Guangzhou Biobank Cohort Study (2003-8) to examine the adjusted association of early life (

Original language	English
Pages (from-to)	e19675
Journal	PLoS ONE
Volume	6
Issue number	5
DOIs	https://doi.org/10.1371/journal.pone.0019675
Publication status	Published - 1 May 2011

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AU - Cheng, Kar

AU - Leung, GM

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AB - Background: In observational studies from western countries childhood emotional adversity is usually associated with adult cardiovascular disease. These findings are open to contextual biases making evidence from other settings valuable. We examined the association of a potential marker of childhood emotional adversity with cardiovascular disease risk factors in a developing country. Methods: We used multivariable regression in cross-sectional analysis of older (>= 50 years) men (n = 7,885) and women (n = 20,886) from the Guangzhou Biobank Cohort Study (2003-8) to examine the adjusted association of early life (

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Parental Death during Childhood and Adult Cardiovascular Risk in a Developing Country: The Guangzhou Biobank Cohort Study

Abstract

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