Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate

Giordano Pula; Elena Garonna; Warwick B Dunn; Michio Hirano; Giuseppe Pizzorno; Michelangelo Campanella; Edward L Schwartz; Mahmoud H El Kouni; Caroline P D Wheeler-Jones

doi:10.1161/ATVBAHA.110.215855

Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate

Giordano Pula, Elena Garonna, Warwick B Dunn, Michio Hirano, Giuseppe Pizzorno, Michelangelo Campanella, Edward L Schwartz, Mahmoud H El Kouni, Caroline P D Wheeler-Jones

Biosciences

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Micromolar concentrations of the proangiogenic metabolite deoxyribose-1-phosphate (dRP) were detected in platelet supernatants by mass spectrometry. In this study, we assessed whether the release of dRP by platelets stimulates endothelial cell migration and angiogenesis.

Original language	English
Pages (from-to)	2631-8
Number of pages	8
Journal	Arteriosclerosis Thrombosis and Vascular Biology
Volume	30
Issue number	12
DOIs	https://doi.org/10.1161/ATVBAHA.110.215855
Publication status	Published - Dec 2010

Access to Document

10.1161/ATVBAHA.110.215855

Cite this

@article{d95bab3be8c24b4bab47a739140bb9da,

title = "Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate",

abstract = "Micromolar concentrations of the proangiogenic metabolite deoxyribose-1-phosphate (dRP) were detected in platelet supernatants by mass spectrometry. In this study, we assessed whether the release of dRP by platelets stimulates endothelial cell migration and angiogenesis.",

author = "Giordano Pula and Elena Garonna and Dunn, \{Warwick B\} and Michio Hirano and Giuseppe Pizzorno and Michelangelo Campanella and Schwartz, \{Edward L\} and \{El Kouni\}, \{Mahmoud H\} and Wheeler-Jones, \{Caroline P D\}",

year = "2010",

month = dec,

doi = "10.1161/ATVBAHA.110.215855",

language = "English",

volume = "30",

pages = "2631--8",

journal = "Arteriosclerosis Thrombosis and Vascular Biology",

issn = "1524-4636",

publisher = "American Heart Association",

number = "12",

}

TY - JOUR

T1 - Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate

AU - Pula, Giordano

AU - Garonna, Elena

AU - Dunn, Warwick B

AU - Hirano, Michio

AU - Pizzorno, Giuseppe

AU - Campanella, Michelangelo

AU - Schwartz, Edward L

AU - El Kouni, Mahmoud H

AU - Wheeler-Jones, Caroline P D

PY - 2010/12

Y1 - 2010/12

N2 - Micromolar concentrations of the proangiogenic metabolite deoxyribose-1-phosphate (dRP) were detected in platelet supernatants by mass spectrometry. In this study, we assessed whether the release of dRP by platelets stimulates endothelial cell migration and angiogenesis.

AB - Micromolar concentrations of the proangiogenic metabolite deoxyribose-1-phosphate (dRP) were detected in platelet supernatants by mass spectrometry. In this study, we assessed whether the release of dRP by platelets stimulates endothelial cell migration and angiogenesis.

U2 - 10.1161/ATVBAHA.110.215855

DO - 10.1161/ATVBAHA.110.215855

M3 - Article

C2 - 20884872

SN - 1524-4636

VL - 30

SP - 2631

EP - 2638

JO - Arteriosclerosis Thrombosis and Vascular Biology

JF - Arteriosclerosis Thrombosis and Vascular Biology

IS - 12

ER -

Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate

Abstract

Access to Document

Fingerprint

Cite this