TY - JOUR
T1 - Paracetamol poisoning unmasking factor VII deficiency
AU - Chilton, AP
AU - Hussain, T
AU - Elias, Elwyn
PY - 2002/4/1
Y1 - 2002/4/1
N2 - We report on an 18-year-old woman who took an impulsive overdose of paracetamol. The admission international normalized ratio (INR) was prolonged which resulted in her being transferred to a specialist hepatology unit Her clinical condition and laboratory parameters did not correlate; this prompted investigation into her coagulation profile, which revealed a factor VII deficiency and explained the observed abnormalities of an elevated INR, normal partial thromboplastin time and normal liver function. There are no other reports of factor VII deficiency being identified as a result of paracetamol overdose. (C) 2002 Lippincott Williams Wilkins.
AB - We report on an 18-year-old woman who took an impulsive overdose of paracetamol. The admission international normalized ratio (INR) was prolonged which resulted in her being transferred to a specialist hepatology unit Her clinical condition and laboratory parameters did not correlate; this prompted investigation into her coagulation profile, which revealed a factor VII deficiency and explained the observed abnormalities of an elevated INR, normal partial thromboplastin time and normal liver function. There are no other reports of factor VII deficiency being identified as a result of paracetamol overdose. (C) 2002 Lippincott Williams Wilkins.
UR - http://www.scopus.com/inward/record.url?scp=0036228347&partnerID=8YFLogxK
U2 - 10.1097/00042737-200204000-00019
DO - 10.1097/00042737-200204000-00019
M3 - Article
C2 - 11943961
VL - 14
SP - 441
EP - 443
JO - European Journal of Gastroenterology & Hepatology
JF - European Journal of Gastroenterology & Hepatology
IS - (4)
ER -