Paracetamol poisoning unmasking factor VII deficiency

AP Chilton, T Hussain, Elwyn Elias

Research output: Contribution to journalArticle

1 Citation (Scopus)


We report on an 18-year-old woman who took an impulsive overdose of paracetamol. The admission international normalized ratio (INR) was prolonged which resulted in her being transferred to a specialist hepatology unit Her clinical condition and laboratory parameters did not correlate; this prompted investigation into her coagulation profile, which revealed a factor VII deficiency and explained the observed abnormalities of an elevated INR, normal partial thromboplastin time and normal liver function. There are no other reports of factor VII deficiency being identified as a result of paracetamol overdose. (C) 2002 Lippincott Williams Wilkins.
Original languageEnglish
Pages (from-to)441-443
Number of pages3
JournalEuropean Journal of Gastroenterology & Hepatology
Issue number(4)
Publication statusPublished - 1 Apr 2002


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