Overrepresentation of the Fcgamma receptor type IIA R131/R131 genotype in caucasoid systemic lupus erythematosus patients with autoantibodies to C1q and glomerulonephritis

P Norsworthy, E Theodoridis, M Botto, P Athanassiou, H Beynon, C Gordon, D Isenberg, M J Walport, K A Davies

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81 Citations (Scopus)

Abstract

To test the hypothesis that there is an association between the Fcgamma receptor type IIA (FcgammaRIIA)-H/R131 polymorphism and autoantibodies to the collagenous region (CLR) of C1q in patients with systemic lupus erythematosus (SLE).
Original languageEnglish
Pages (from-to)1828-32
Number of pages5
JournalArthritis & Rheumatism
Volume42
Issue number9
DOIs
Publication statusPublished - Sep 1999

Keywords

  • Alleles
  • Autoantibodies
  • Cohort Studies
  • Complement C1q
  • European Continental Ancestry Group
  • Gene Frequency
  • Genotype
  • Heterozygote
  • Homozygote
  • Humans
  • Immunoglobulin G
  • Lupus Erythematosus, Systemic
  • Lupus Nephritis
  • Receptors, IgG

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