Outcomes of cardiac surgery in Jehovah's Witness patients: A review

Aimee-Louise Chambault, Louise J Brown, Sophie Mellor, Amer Harky*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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OBJECTIVE: To review current literature evidence on outcomes of cardiac surgery in Jehovah's Witness patients.

METHODS: A comprehensive electronic literature search was done from 2010 to 20th August 2020 identifying articles that discussed optimisation/outcomes of cardiac surgery in Jehovah's Witness either as a solo cohort or as comparative to non-Jehovah's Witnesses. No limit was placed on place of publication and the evidence has been summarised in a narrative manner within the manuscript.

RESULTS: The outcomes of cardiac surgery in Jehovah's Witness patients has been described, and also compared, to non-Witness patients within a number of case reports, case series and comparative cohort studies. Many of these studies note no significant differences between outcomes of the two groups for a number of variables, including mortality. Pre-, intra and post-operative optimisation of the patients by a multidisciplinary team is important to achieve good outcomes.

CONCLUSION: The use of a bloodless protocol for Jehovah's Witnesses does not appear to significantly impact upon clinical outcomes when compared to non-Witness patients, and it has even been suggested that a bloodless approach could provide advantages to all patients undergoing cardiac surgery. Larger cohorts and research across multiple centres into the long term outcomes of these patients is required.

Original languageEnglish
Pages (from-to)267659120980375
Early online date16 Dec 2020
Publication statusE-pub ahead of print - 16 Dec 2020


  • Jehovah’s Witness
  • bloodless surgery
  • transfusion
  • outcomes
  • cardiac surgery
  • blood products


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