Open chromatin and hypertranscription in embryonic stem cells

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11 Citations (Scopus)

Abstract

In this issue of Cell Stem Cell, Efroni et al. (2008) use tiling microarrays to reveal genome-wide hypertranscription in mouse embryonic stem cells (ESCs), including expression of normally silent, noncoding regions. Hypertranscription may reflect the unusual "open" structure of ESC chromatin.
Original languageEnglish
Pages (from-to)408-10
Number of pages3
JournalCell stem cell
Volume2
Issue number5
DOIs
Publication statusPublished - 8 May 2008

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