One-pot synthesis of a new generation of hybrid bisphosphonate polyoxometalate gold nanoparticles as antibiofilm agents

S. Tomane; E. López-Maya; S. Boujday; V. Humblot; J. Marrot; N. Rabasso; J. Castells-Gil; C. Sicard; A. Dolbecq; P. Mialane; A. Vallée

doi:10.1039/c9na00401g

One-pot synthesis of a new generation of hybrid bisphosphonate polyoxometalate gold nanoparticles as antibiofilm agents

S. Tomane
, E. López-Maya
, S. Boujday
, V. Humblot
, J. Marrot
, N. Rabasso
, J. Castells-Gil
, C. Sicard
, A. Dolbecq
, P. Mialane
, A. Vallée^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Letter › peer-review

Abstract

A reduced polyoxovanadate functionalized with bisphosphonate molecules was synthesized and used to prepare in one step hybrid organic-inorganic polyoxometalate decorated gold nanoparticles. These new composites were shown to strongly inhibit P. aeruginosa and S. epidermidis biofilm growth, with the three components constituting the nanoparticles (Au⁰ core, vanadium and alendronate) acting synergistically.

Original language	English
Pages (from-to)	3400-3405
Number of pages	6
Journal	Nanoscale Advances
Volume	1
Issue number	9
Early online date	29 Jul 2019
DOIs	https://doi.org/10.1039/c9na00401g
Publication status	Published - 1 Sept 2019

Bibliographical note

Publisher Copyright:
© 2019 The Royal Society of Chemistry.

ASJC Scopus subject areas

Bioengineering
Atomic and Molecular Physics, and Optics
General Chemistry
General Materials Science
General Engineering

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10.1039/c9na00401gLicence: Creative Commons: Attribution-NonCommercial (CC BY-NC)

Cite this

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title = "One-pot synthesis of a new generation of hybrid bisphosphonate polyoxometalate gold nanoparticles as antibiofilm agents",

abstract = "A reduced polyoxovanadate functionalized with bisphosphonate molecules was synthesized and used to prepare in one step hybrid organic-inorganic polyoxometalate decorated gold nanoparticles. These new composites were shown to strongly inhibit P. aeruginosa and S. epidermidis biofilm growth, with the three components constituting the nanoparticles (Au0 core, vanadium and alendronate) acting synergistically.",

author = "S. Tomane and E. L{\'o}pez-Maya and S. Boujday and V. Humblot and J. Marrot and N. Rabasso and J. Castells-Gil and C. Sicard and A. Dolbecq and P. Mialane and A. Vall{\'e}e",

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doi = "10.1039/c9na00401g",

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T1 - One-pot synthesis of a new generation of hybrid bisphosphonate polyoxometalate gold nanoparticles as antibiofilm agents

AU - Tomane, S.

AU - López-Maya, E.

AU - Boujday, S.

AU - Humblot, V.

AU - Marrot, J.

AU - Rabasso, N.

AU - Castells-Gil, J.

AU - Sicard, C.

AU - Dolbecq, A.

AU - Mialane, P.

AU - Vallée, A.

PY - 2019/9/1

Y1 - 2019/9/1

N2 - A reduced polyoxovanadate functionalized with bisphosphonate molecules was synthesized and used to prepare in one step hybrid organic-inorganic polyoxometalate decorated gold nanoparticles. These new composites were shown to strongly inhibit P. aeruginosa and S. epidermidis biofilm growth, with the three components constituting the nanoparticles (Au0 core, vanadium and alendronate) acting synergistically.

AB - A reduced polyoxovanadate functionalized with bisphosphonate molecules was synthesized and used to prepare in one step hybrid organic-inorganic polyoxometalate decorated gold nanoparticles. These new composites were shown to strongly inhibit P. aeruginosa and S. epidermidis biofilm growth, with the three components constituting the nanoparticles (Au0 core, vanadium and alendronate) acting synergistically.

UR - https://www.scopus.com/pages/publications/85072208302

U2 - 10.1039/c9na00401g

DO - 10.1039/c9na00401g

M3 - Letter

AN - SCOPUS:85072208302

SN - 2516-0230

VL - 1

SP - 3400

EP - 3405

JO - Nanoscale Advances

JF - Nanoscale Advances

IS - 9

ER -

One-pot synthesis of a new generation of hybrid bisphosphonate polyoxometalate gold nanoparticles as antibiofilm agents

Abstract

Bibliographical note

ASJC Scopus subject areas

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