On the origin of oscillopsia during pedunculopontine stimulation

Ned Jenkinson, John-Stuart Brittain, Stephen L Hicks, Christopher Kennard, Tipu Z Aziz

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


We report a case of induced oscillopsia caused by deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN). Recent reports have described involuntary oscillopsia during DBS of the PPN that patients have described as trembling vision. Here we substantiate this observation using infra-red eye tracking. It has been suggested that this phenomenon might be used as an indicator of accurate targeting of the PPN with DBS. Our observations suggest that this phenomenon may not be related to a constricted anatomical structure and therefore such practise may be unwise. Scrutiny has led us to believe that the oscillopsia in our patient is not caused by direct stimulation of the oculomotor nerve as suggested in a previous report, but by stimulation of fibres in the uncinate fasciculus of the cerebellum and the superior cerebellar peduncle, which in turn stimulate the saccadic pre-motor neurones in the brainstem.

Original languageEnglish
Pages (from-to)124-9
Number of pages6
JournalStereotactic and Functional Neurosurgery
Issue number2
Publication statusPublished - 2012


  • Deep Brain Stimulation
  • Humans
  • Male
  • Middle Aged
  • Ocular Motility Disorders
  • Parkinson Disease
  • Pedunculopontine Tegmental Nucleus
  • Journal Article


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