National differences in publishing papers on adverse drug reactions

Robin Ferner, JK Aronson

Research output: Contribution to journalArticle

13 Citations (Scopus)


AIMS: To examine how countries differ in attitudes to adverse drug reactions by examining published scientific papers. METHODS: We searched Ovid EMBASE for publications indexed by the category "therapeutic agents", and the subcategory "adverse effects", by country for 43 countries. RESULTS: We counted 1 810 202 papers world-wide regarding therapeutic agents during 14 years, of which 195 154 (10.8%) were included in the adverse effects subcategory. There were substantial differences between countries, not explained by population, economic variation, overall publication rate on therapeutic agents, or the presence of large indigenous pharmaceutical companies. CONCLUSIONS: Many local cultural factors influence the ratio of papers on adverse reactions to all drug effects, so it may be difficult to improve their recognition and reporting by international efforts.
Original languageEnglish
Pages (from-to)108-11
Number of pages4
JournalBritish Journal of Clinical Pharmacology
Issue number1
Publication statusPublished - 1 Jan 2005


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