Abstract
Fluoroquinolone-resistant Escherichia coli isolates which overexpressed acrB and had a substitution at amino acid 45 of AcrR were complemented with wild-type acrR. Complementation led to increased sensitivity to ciprofloxacin and to ethidium bromide, suggesting that mutation at amino acid 45 of AcrR contributes to ciprofloxacin resistance.
Original language | English |
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Pages (from-to) | 4390-92 |
Number of pages | 3 |
Journal | Antimicrobial Agents and Chemotherapy |
Volume | 49 |
DOIs | |
Publication status | Published - 1 Jan 2005 |