Abstract
Mutation of the HMG-CoA synthase encoding mupH gene in Pseudomonas fluorescens gives rise to a new metabolite formed from a truncated polyketide intermediate, providing in vivo evidence for the roles of mupH and cognate genes found in several "AT-less" and other bacterial PKS gene clusters responsible for the biosynthesis of diverse metabolites containing acetate/propionate derived side chains.
Original language | English |
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Pages (from-to) | 2040-2042 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 20 |
DOIs | |
Publication status | Published - 1 Jan 2007 |