Multistep DNA-Templated Reactions for the Synthesis of Functional Sequence Controlled Oligomers

Mireya L. McKee; Phillip J. Milnes; Jonathan Bath; Eugen Stulz; Andrew J. Turberfield; Rachel K. O'Reilly

doi:10.1002/anie.201002721

Multistep DNA-Templated Reactions for the Synthesis of Functional Sequence Controlled Oligomers

Mireya L. McKee, Phillip J. Milnes, Jonathan Bath, Eugen Stulz, Andrew J. Turberfield, Rachel K. O'Reilly

Chemistry

Research output: Contribution to journal › Article › peer-review

108 Citations (Scopus)

Abstract

Biomimetic: A strand displacement mechanism was designed to permit DNA-templated synthesis of functional oligomers of arbitrary length (see scheme). Key features of the mechanism are that successive coupling reactions take place in near-identical environments and that purification is only necessary in the last synthesis step.

Original language	English
Pages (from-to)	7984-7951
Journal	Angewandte Chemie (International Edition)
Volume	49
Issue number	43
DOIs	https://doi.org/10.1002/anie.201002721
Publication status	Published - 10 Sept 2010

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abstract = "Biomimetic: A strand displacement mechanism was designed to permit DNA-templated synthesis of functional oligomers of arbitrary length (see scheme). Key features of the mechanism are that successive coupling reactions take place in near-identical environments and that purification is only necessary in the last synthesis step.",

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AU - Stulz, Eugen

AU - Turberfield, Andrew J.

AU - O'Reilly, Rachel K.

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Multistep DNA-Templated Reactions for the Synthesis of Functional Sequence Controlled Oligomers

Abstract

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