Multiple depositions of Ag nanoparticles on chemically modified agarose films for surface-enhanced Raman spectroscopy

Wen Lei Zhai; Da Wei Li; Lu Lu Qu; John S. Fossey; Yi Tao Long

doi:10.1039/c1nr10956a

Multiple depositions of Ag nanoparticles on chemically modified agarose films for surface-enhanced Raman spectroscopy

Wen Lei Zhai, Da Wei Li, Lu Lu Qu, John S. Fossey, Yi Tao Long^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

71 Citations (Scopus)

Abstract

A facile and cost-effective approach for the preparation of a surface-enhanced Raman spectroscopy (SERS) substrate through constructing silver nanoparticle/3-aminopropyltriethoxysilane/agarose films (Ag NPs/APTES/Agar film) on various solid supports is described. The SERS performance of the substrate was systematically investigated, revealing a maximum SERS intensity with four layers of the Ag NP deposition. The enhancement factor of the developed substrate was calculated as 1.5 × 10 ⁷ using rhodamine 6G (R6G) as the probe molecule, and the reproducibility of the SERS signals was established. A high throughput screening platform was designed, manufactured and implemented which utilised the ability to cast agarose to assemble arrays. Quantitative analysis of 4-aminobenzoic acid (4-ABA) and 4-aminothiophenol (4-ATP) was achieved over a ∼0.5 nM-0.1 μM range.

Original language	English
Pages (from-to)	137-142
Number of pages	6
Journal	Nanoscale
Volume	4
Issue number	1
DOIs	https://doi.org/10.1039/c1nr10956a
Publication status	Published - 7 Jan 2012

ASJC Scopus subject areas

General Materials Science

Access to Document

10.1039/c1nr10956a

Cite this

@article{36ad40e3e7c44675abf169025967ed45,

title = "Multiple depositions of Ag nanoparticles on chemically modified agarose films for surface-enhanced Raman spectroscopy",

abstract = "A facile and cost-effective approach for the preparation of a surface-enhanced Raman spectroscopy (SERS) substrate through constructing silver nanoparticle/3-aminopropyltriethoxysilane/agarose films (Ag NPs/APTES/Agar film) on various solid supports is described. The SERS performance of the substrate was systematically investigated, revealing a maximum SERS intensity with four layers of the Ag NP deposition. The enhancement factor of the developed substrate was calculated as 1.5 × 10 7 using rhodamine 6G (R6G) as the probe molecule, and the reproducibility of the SERS signals was established. A high throughput screening platform was designed, manufactured and implemented which utilised the ability to cast agarose to assemble arrays. Quantitative analysis of 4-aminobenzoic acid (4-ABA) and 4-aminothiophenol (4-ATP) was achieved over a ∼0.5 nM-0.1 μM range.",

author = "Zhai, {Wen Lei} and Li, {Da Wei} and Qu, {Lu Lu} and Fossey, {John S.} and Long, {Yi Tao}",

year = "2012",

month = jan,

day = "7",

doi = "10.1039/c1nr10956a",

language = "English",

volume = "4",

pages = "137--142",

journal = "Nanoscale",

issn = "2040-3364",

publisher = "Royal Society of Chemistry",

number = "1",

}

TY - JOUR

T1 - Multiple depositions of Ag nanoparticles on chemically modified agarose films for surface-enhanced Raman spectroscopy

AU - Zhai, Wen Lei

AU - Li, Da Wei

AU - Qu, Lu Lu

AU - Fossey, John S.

AU - Long, Yi Tao

PY - 2012/1/7

Y1 - 2012/1/7

N2 - A facile and cost-effective approach for the preparation of a surface-enhanced Raman spectroscopy (SERS) substrate through constructing silver nanoparticle/3-aminopropyltriethoxysilane/agarose films (Ag NPs/APTES/Agar film) on various solid supports is described. The SERS performance of the substrate was systematically investigated, revealing a maximum SERS intensity with four layers of the Ag NP deposition. The enhancement factor of the developed substrate was calculated as 1.5 × 10 7 using rhodamine 6G (R6G) as the probe molecule, and the reproducibility of the SERS signals was established. A high throughput screening platform was designed, manufactured and implemented which utilised the ability to cast agarose to assemble arrays. Quantitative analysis of 4-aminobenzoic acid (4-ABA) and 4-aminothiophenol (4-ATP) was achieved over a ∼0.5 nM-0.1 μM range.

AB - A facile and cost-effective approach for the preparation of a surface-enhanced Raman spectroscopy (SERS) substrate through constructing silver nanoparticle/3-aminopropyltriethoxysilane/agarose films (Ag NPs/APTES/Agar film) on various solid supports is described. The SERS performance of the substrate was systematically investigated, revealing a maximum SERS intensity with four layers of the Ag NP deposition. The enhancement factor of the developed substrate was calculated as 1.5 × 10 7 using rhodamine 6G (R6G) as the probe molecule, and the reproducibility of the SERS signals was established. A high throughput screening platform was designed, manufactured and implemented which utilised the ability to cast agarose to assemble arrays. Quantitative analysis of 4-aminobenzoic acid (4-ABA) and 4-aminothiophenol (4-ATP) was achieved over a ∼0.5 nM-0.1 μM range.

UR - http://www.scopus.com/inward/record.url?scp=83455195481&partnerID=8YFLogxK

U2 - 10.1039/c1nr10956a

DO - 10.1039/c1nr10956a

M3 - Article

C2 - 22064940

AN - SCOPUS:83455195481

SN - 2040-3364

VL - 4

SP - 137

EP - 142

JO - Nanoscale

JF - Nanoscale

IS - 1

ER -

Multiple depositions of Ag nanoparticles on chemically modified agarose films for surface-enhanced Raman spectroscopy

Abstract

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this