Multiple cytotoxic and genotoxic effects induced in vitro by differently shaped copper oxide nanomaterials

Keyphrases

• Cytotoxic Effect 100%
• Genotoxic Effect 100%
• Copper Oxide Nanoparticles (CuO NPs) 100%
• Copper Oxide Nanomaterials 100%
• Cytotoxicity 60%
• Comet Assay 40%
• Genotoxicity 40%
• Oxidative DNA Damage 40%
• Nanotoxicology 40%
• Aneugenic 40%
• Nanoparticles 20%
• Significant Trend 20%
• Cytotoxic Activity 20%
• Size-and-shape 20%
• Murine Macrophages 20%
• Dose Effect 20%
• Positive Control 20%
• Peripheral Blood 20%
• Cytostasis 20%
• Fluorescence in Situ Hybridization 20%
• Peripheral Blood Lymphocytes 20%
• Healthy Volunteers 20%
• Cell Viability 20%
• Proliferative Activity 20%
• DNA Double-strand Breaks 20%
• Formazan 20%
• Two-cell 20%
• Dose-response Relationship 20%
• Pyrimidine 20%
• Mass Concentration 20%
• Time Characteristics 20%
• MTT Assay 20%
• Genotoxic Potential 20%
• Purine 20%
• RAW264.7 Cells 20%
• Apoptotic Markers 20%
• In Vivo Exposure 20%
• Colorimetric Assay 20%
• Activity Markers 20%
• Micronucleus 20%
• RAW264.7 Macrophages 20%
• CuO Nanoparticles 20%
• Clastogenic 20%
• Cytokinesis-block Micronucleus Assay 20%
• 3-(4,5-dimethylthiazol-2-yl)-2 20%
• Primary DNA Damage 20%
• 5-diphenyltetrazolium Bromide 20%
• Binucleated Cells 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Nanomaterial 100%
• Cytotoxicity 100%
• Copper Oxide 100%
• Comet Assay 66%
• Genotoxicity 66%
• Nanotoxicology 66%
• Normal Human 33%
• Nanoparticle 33%
• Formazan 33%
• Cell Viability 33%
• 3 (4,5 Dimethyl 2 Thiazolyl) 2,5 Diphenyltetrazolium Bromide 33%
• Copper Oxide Nanoparticle 33%
• Purine Derivative 33%
• Pyrimidine Derivative 33%