Mortality of patients with Cushing’s disease

Georgia Ntali, Osamah Hakami, Milanka Wattegama, Shahzada Ahmed, Niki Karavitaki

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)
90 Downloads (Pure)

Abstract

Cushing’s disease is a rare condition of cortisol excess attributed to a pituitary adenoma with an annual incidence of 1.2–2.4 cases per million population. It is associated with several co-morbidities leading to increased mortality predominantly due to cardiovascular disease. Despite the advances in its diagnosis and management, survival can be compromised even after apparent successful treatment. Minimizing the duration and extent of exposure to hypercortisolaemia by early diagnosis and rapid, effective therapeutic interventions, as well as close monitoring and aggressive control of cardiovascular risk factors are vital for improving outcomes of the patients.
Original languageEnglish
JournalExperimental and Clinical Endocrinology and Diabetes
Early online date9 Jul 2020
DOIs
Publication statusE-pub ahead of print - 9 Jul 2020

Keywords

  • Cushing's disease
  • cortisol excess
  • mortality
  • survival
  • remission
  • cardiovascular risk

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