Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

D. J. Nieves; N. S. Azmi; R. Xu; R. Levy; E. A. Yates; D. G. Fernig

doi:10.1039/c4cc05909c

Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

D. J. Nieves, N. S. Azmi, R. Xu, R. Levy, E. A. Yates, D. G. Fernig

Immunology and Immunotherapy

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Abstract

A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.

Original language	English
Pages (from-to)	13157-13160
Number of pages	4
Journal	Chemical Communications
Issue number	86
DOIs	https://doi.org/10.1039/c4cc05909c
Publication status	Published - 9 Sept 2014

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https://doi.org/10.1039/C4CC05909CLicence: Creative Commons: Attribution (CC BY)

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title = "Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry",

abstract = "A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.",

author = "Nieves, {D. J.} and Azmi, {N. S.} and R. Xu and R. Levy and Yates, {E. A.} and Fernig, {D. G.}",

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AU - Levy, R.

AU - Yates, E. A.

AU - Fernig, D. G.

PY - 2014/9/9

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DO - 10.1039/c4cc05909c

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JO - Chemical Communications

JF - Chemical Communications

IS - 86

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Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

Abstract

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