Modelling the human immune response: can mice be trusted?

John Gordon, Gillian Grafton, Philip Wood, M Larche, R Armitage

Research output: Contribution to journalArticle

21 Citations (Scopus)


The mouse is now the animal of choice for laboratory-based medical research. Although its contribution to advancing understanding of our inner workings is indisputable, we should acknowledge that mice and humans are tangibly different. This article highlights, and attempts some rationale for, discrepancies between the two species' immune systems.
Original languageEnglish
Pages (from-to)431-435
Number of pages5
JournalCurrent Opinion in Pharmacology
Publication statusPublished - 1 Jan 2001


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