Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement

Vasileios Chortis, Angela E Taylor, Petra Schneider, Jeremy W Tomlinson, Beverly A Hughes, Donna M O'Neil, Rossella Libé, Bruno Allolio, Xavier Bertagna, Jérôme Bertherat, Felix Beuschlein, Martin Fassnacht, Niki Karavitaki, Massimo Mannelli, Franco Mantero, Giuseppe Opocher, Emilio Porfiri, Marcus Quinkler, Mark Sherlock, Massimo TerzoloPeter Nightingale, Cedric H L Shackleton, Paul M Stewart, Stefanie Hahner, Wiebke Arlt

Research output: Contribution to journalArticlepeer-review

90 Citations (Scopus)
709 Downloads (Pure)

Fingerprint

Dive into the research topics of 'Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement'. Together they form a unique fingerprint.

Medicine & Life Sciences

Chemistry