Microwave-to-terahertz dielectric resonators for liquid sensing in microfluidic systems

N. Klein, C. Watts, S. M. Hanham, W. J. Otter, M. M. Ahmad, S. Lucyszyn

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The microwave-to-terahertz frequency range offers unique opportunities for the sensing of liquids based on the degree of molecular orientational and electronic polarization, Debye relaxation due to intermolecular forces between (semi-)polar molecules and collective vibrational modes within complex molecules. Methods for the fast dielectric characterization of (sub-)nanolitre volumes of mostly aqueous liquids and biological cell suspensions are discussed, with emphasis on labon-chip approaches aimed towards single-cell detection and label-free flow cytometry at microwave-to-terahertz frequencies. Among the most promising approaches, photonic crystal defect cavities made from high-resistivity silicon are compared with metallic split-ring resonant systems and high quality factor (Q-factor) whispering gallery-type resonances in dielectric resonators. Applications range from accurate haemoglobin measurements on nanolitre samples to label-free detection of circulating tumor cells.

Original languageEnglish
Title of host publicationTerahertz Emitters, Receivers, and Applications VII
EditorsManijeh Razeghi, Alexei N. Baranov, John M. Zavada, Dimitris Pavlidis
PublisherSociety of Photo-Optical Instrumentation Engineers
ISBN (Electronic)9781510602595
DOIs
Publication statusPublished - 26 Sep 2016
EventTerahertz Emitters, Receivers, and Applications VII - San Diego, United States
Duration: 28 Aug 201631 Aug 2016

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume9934
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceTerahertz Emitters, Receivers, and Applications VII
Country/TerritoryUnited States
CitySan Diego
Period28/08/1631/08/16

Keywords

  • dielectric resonators
  • label free cancer cell detection
  • microwave and terahertz liquid characterization
  • photonic crystal resonators

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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