Microwave enhanced reaction of carbohydrates with amino-derivatised labels and glass surfaces

Edwin Yates; Martin Jones; Carl Clarke; AK Powell; Simon Johnson; A Porch; Peter Edwards; Jeremy Turnbull

doi:10.1039/b305248f

Microwave enhanced reaction of carbohydrates with amino-derivatised labels and glass surfaces

Edwin Yates, Martin Jones, Carl Clarke, AK Powell, Simon Johnson, A Porch, Peter Edwards, Jeremy Turnbull

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35 Citations (Scopus)

Abstract

The reaction between carbohydrates and amino-derivatised labels has been improved through microwave heating. We show it proceeds principally via solvent mediated heating rather than either direct microwave heating of the reagents or microwave influenced changes in the rates of mutarotation in the sugars beyond those obtained by conventional thermal heating. The method is applied to the attachment of sugars to an aminosilane-derivatised glass surface suitable for the construction of carbohydrate microarrays.

Original language	English
Pages (from-to)	2061-2063
Number of pages	3
Journal	Journal of Materials Chemistry
Volume	13
Issue number	9
DOIs	https://doi.org/10.1039/b305248f
Publication status	Published - 1 Jan 2003

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title = "Microwave enhanced reaction of carbohydrates with amino-derivatised labels and glass surfaces",

abstract = "The reaction between carbohydrates and amino-derivatised labels has been improved through microwave heating. We show it proceeds principally via solvent mediated heating rather than either direct microwave heating of the reagents or microwave influenced changes in the rates of mutarotation in the sugars beyond those obtained by conventional thermal heating. The method is applied to the attachment of sugars to an aminosilane-derivatised glass surface suitable for the construction of carbohydrate microarrays.",

author = "Edwin Yates and Martin Jones and Carl Clarke and AK Powell and Simon Johnson and A Porch and Peter Edwards and Jeremy Turnbull",

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AU - Yates, Edwin

AU - Jones, Martin

AU - Clarke, Carl

AU - Powell, AK

AU - Johnson, Simon

AU - Porch, A

AU - Edwards, Peter

AU - Turnbull, Jeremy

PY - 2003/1/1

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N2 - The reaction between carbohydrates and amino-derivatised labels has been improved through microwave heating. We show it proceeds principally via solvent mediated heating rather than either direct microwave heating of the reagents or microwave influenced changes in the rates of mutarotation in the sugars beyond those obtained by conventional thermal heating. The method is applied to the attachment of sugars to an aminosilane-derivatised glass surface suitable for the construction of carbohydrate microarrays.

AB - The reaction between carbohydrates and amino-derivatised labels has been improved through microwave heating. We show it proceeds principally via solvent mediated heating rather than either direct microwave heating of the reagents or microwave influenced changes in the rates of mutarotation in the sugars beyond those obtained by conventional thermal heating. The method is applied to the attachment of sugars to an aminosilane-derivatised glass surface suitable for the construction of carbohydrate microarrays.

U2 - 10.1039/b305248f

DO - 10.1039/b305248f

M3 - Article

VL - 13

SP - 2061

EP - 2063

JO - Journal of Materials Chemistry

JF - Journal of Materials Chemistry

IS - 9

ER -

Microwave enhanced reaction of carbohydrates with amino-derivatised labels and glass surfaces

Abstract

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