Microbiome-mediated colonization resistance to and countermeasures of Klebsiella pneumoniae

Yongqiang Yang; Willem van Schaik; Alan McNally; Zhiyong Zong

doi:10.1038/s41467-026-69690-9

Microbiome-mediated colonization resistance to and countermeasures of Klebsiella pneumoniae

Yongqiang Yang
, Willem van Schaik
, Alan McNally
, Zhiyong Zong^*

^*Corresponding author for this work

Microbes, Infection and Microbiomes

Research output: Contribution to journal › Article › peer-review

Abstract

Klebsiella pneumoniae intestinal colonization contributes to infectious and non-infectious diseases. Recent studies have uncovered the complex interplay between the gut microbiota and K. pneumoniae colonization, highlighting its role in disease development and progression and illustrating the potential of microbiome-based therapies.

Original language	English
Article number	1761
Number of pages	5
Journal	Nature Communications
Volume	17
Early online date	16 Feb 2026
DOIs	https://doi.org/10.1038/s41467-026-69690-9
Publication status	Published - 17 Feb 2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1038/s41467-026-69690-9Licence: Creative Commons: Attribution (CC BY)

YangY2026MicrobiomeMediatedFinal published version, 675 KBLicence: Creative Commons: Attribution (CC BY)

DETECTIVE: Dissemination and resistance mechanisms of carbapenem-resistant Gram-negative bacilli
van Schaik, W. (Co-Investigator) & McNally, A. (Principal Investigator)
Medical Research Council
14/02/19 → 31/03/23
Project: Research Councils

Cite this

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title = "Microbiome-mediated colonization resistance to and countermeasures of Klebsiella pneumoniae",

abstract = " Klebsiella pneumoniae intestinal colonization contributes to infectious and non-infectious diseases. Recent studies have uncovered the complex interplay between the gut microbiota and K. pneumoniae colonization, highlighting its role in disease development and progression and illustrating the potential of microbiome-based therapies. ",

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AU - McNally, Alan

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Y1 - 2026/2/17

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AB - Klebsiella pneumoniae intestinal colonization contributes to infectious and non-infectious diseases. Recent studies have uncovered the complex interplay between the gut microbiota and K. pneumoniae colonization, highlighting its role in disease development and progression and illustrating the potential of microbiome-based therapies.

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JO - Nature Communications

JF - Nature Communications

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Microbiome-mediated colonization resistance to and countermeasures of Klebsiella pneumoniae

Abstract

UN SDGs

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Projects

DETECTIVE: Dissemination and resistance mechanisms of carbapenem-resistant Gram-negative bacilli

Cite this