Mechanomicrobiology: How Mechanical Forces Activate Staphylococcus aureus Adhesion.

JA Geoghegan; YF Dufrêne

doi:10.1016/j.tim.2018.05.004

Mechanomicrobiology: How Mechanical Forces Activate Staphylococcus aureus Adhesion.

JA Geoghegan
, YF Dufrêne

Microbes, Infection and Microbiomes

Research output: Contribution to journal › Article › peer-review

Abstract

During colonization of biomaterials and host tissues, surface-attached bacteria are subjected to mechanical stresses, including hydrodynamic flow and cell-surface contacts. Two publications show that mechanical force activates the adhesive function of Staphylococcus aureus surface proteins, thereby providing the pathogen with a means to withstand high shear stress during colonization.

Original language	English
Pages (from-to)	645-648
Journal	Trends in Microbiology
Volume	26
Issue number	8
DOIs	https://doi.org/10.1016/j.tim.2018.05.004
Publication status	Published - Jun 2018

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title = "Mechanomicrobiology: How Mechanical Forces Activate Staphylococcus aureus Adhesion.",

abstract = "During colonization of biomaterials and host tissues, surface-attached bacteria are subjected to mechanical stresses, including hydrodynamic flow and cell-surface contacts. Two publications show that mechanical force activates the adhesive function of Staphylococcus aureus surface proteins, thereby providing the pathogen with a means to withstand high shear stress during colonization.",

author = "JA Geoghegan and YF Dufr{\^e}ne",

year = "2018",

month = jun,

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volume = "26",

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AU - Geoghegan, JA

AU - Dufrêne, YF

PY - 2018/6

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N2 - During colonization of biomaterials and host tissues, surface-attached bacteria are subjected to mechanical stresses, including hydrodynamic flow and cell-surface contacts. Two publications show that mechanical force activates the adhesive function of Staphylococcus aureus surface proteins, thereby providing the pathogen with a means to withstand high shear stress during colonization.

AB - During colonization of biomaterials and host tissues, surface-attached bacteria are subjected to mechanical stresses, including hydrodynamic flow and cell-surface contacts. Two publications show that mechanical force activates the adhesive function of Staphylococcus aureus surface proteins, thereby providing the pathogen with a means to withstand high shear stress during colonization.

UR - http://europepmc.org/abstract/med/29866473

U2 - 10.1016/j.tim.2018.05.004

DO - 10.1016/j.tim.2018.05.004

M3 - Article

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SN - 0966-842X

VL - 26

SP - 645

EP - 648

JO - Trends in Microbiology

JF - Trends in Microbiology

IS - 8

ER -

Mechanomicrobiology: How Mechanical Forces Activate Staphylococcus aureus Adhesion.

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