TY - JOUR
T1 - Mechanical properties of biodegradable polymer sutures coated with bioactive glass
AU - Stamboulis, Artemis
AU - Boccaccini, AR
AU - Hench, LL
PY - 2002/1/1
Y1 - 2002/1/1
N2 - Combining commercially available Polyglactin 910 (Vicryl) sutures with bioactive glass powder offers new possibilities for application of composite materials in tissue engineering. Commercial bioactive glass (45S5 Bioglass) powder was used to coat Vicryl sutures and the tensile strength of the sutures was tested before and after immersion in simulated body fluid (SBF) as a means to assess the effect of the bioactive glass coating on suture degradation. Different gauge lengths (126.6 and 111.6 mm) and strain rates (2.54, 11.4 and 25.4 mm/min) were tested. The tensile strength of composite sutures was slightly lower than that of as-received Vicryl sutures (404 MPa versus 463 MPa). However after 28 days immersion in SBF the residual tensile strength of the coated sutures was significantly higher, indicating a protective function of the Bioglass coating. The tensile strength results were similar for the different gauge lengths and strain rates investigated. A qualitative explanation for the effect of bioactive glass coating on polymer degradation is offered.
AB - Combining commercially available Polyglactin 910 (Vicryl) sutures with bioactive glass powder offers new possibilities for application of composite materials in tissue engineering. Commercial bioactive glass (45S5 Bioglass) powder was used to coat Vicryl sutures and the tensile strength of the sutures was tested before and after immersion in simulated body fluid (SBF) as a means to assess the effect of the bioactive glass coating on suture degradation. Different gauge lengths (126.6 and 111.6 mm) and strain rates (2.54, 11.4 and 25.4 mm/min) were tested. The tensile strength of composite sutures was slightly lower than that of as-received Vicryl sutures (404 MPa versus 463 MPa). However after 28 days immersion in SBF the residual tensile strength of the coated sutures was significantly higher, indicating a protective function of the Bioglass coating. The tensile strength results were similar for the different gauge lengths and strain rates investigated. A qualitative explanation for the effect of bioactive glass coating on polymer degradation is offered.
UR - http://www.scopus.com/inward/record.url?scp=0036736395&partnerID=8YFLogxK
U2 - 10.1023/A:1016544211478
DO - 10.1023/A:1016544211478
M3 - Article
C2 - 15348548
SN - 0957-4530
VL - 13
SP - 843
EP - 848
JO - Journal of materials science. Materials in medicine
JF - Journal of materials science. Materials in medicine
ER -