Mass spectrometry in systems biology an introduction

Warwick B Dunn

doi:10.1016/B978-0-12-385118-5.00002-5

Mass spectrometry in systems biology an introduction

Warwick B Dunn

Biosciences

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

The qualitative detection, quantification, and structural characterization of analytes in biological systems are important requirements for objectives to be fulfilled in systems biology research. One analytical tool applied to a multitude of systems biology studies is mass spectrometry, particularly for the study of proteins and metabolites. Here, the role of mass spectrometry in systems biology will be assessed, the advantages and disadvantages discussed, and the instrument configurations available described. Finally, general applications will be briefly reviewed.

Original language	English
Pages (from-to)	15-35
Number of pages	21
Journal	Methods in Enzymology
Volume	500
DOIs	https://doi.org/10.1016/B978-0-12-385118-5.00002-5
Publication status	Published - 2011

Bibliographical note

Access to Document

10.1016/B978-0-12-385118-5.00002-5

Cite this

@article{9c0381db256c44d8bc1bb95377b887db,

title = "Mass spectrometry in systems biology an introduction",

abstract = "The qualitative detection, quantification, and structural characterization of analytes in biological systems are important requirements for objectives to be fulfilled in systems biology research. One analytical tool applied to a multitude of systems biology studies is mass spectrometry, particularly for the study of proteins and metabolites. Here, the role of mass spectrometry in systems biology will be assessed, the advantages and disadvantages discussed, and the instrument configurations available described. Finally, general applications will be briefly reviewed.",

author = "Dunn, \{Warwick B\}",

year = "2011",

doi = "10.1016/B978-0-12-385118-5.00002-5",

language = "English",

volume = "500",

pages = "15--35",

journal = "Methods in Enzymology",

publisher = "Elsevier",

}

TY - JOUR

T1 - Mass spectrometry in systems biology an introduction

AU - Dunn, Warwick B

PY - 2011

Y1 - 2011

N2 - The qualitative detection, quantification, and structural characterization of analytes in biological systems are important requirements for objectives to be fulfilled in systems biology research. One analytical tool applied to a multitude of systems biology studies is mass spectrometry, particularly for the study of proteins and metabolites. Here, the role of mass spectrometry in systems biology will be assessed, the advantages and disadvantages discussed, and the instrument configurations available described. Finally, general applications will be briefly reviewed.

AB - The qualitative detection, quantification, and structural characterization of analytes in biological systems are important requirements for objectives to be fulfilled in systems biology research. One analytical tool applied to a multitude of systems biology studies is mass spectrometry, particularly for the study of proteins and metabolites. Here, the role of mass spectrometry in systems biology will be assessed, the advantages and disadvantages discussed, and the instrument configurations available described. Finally, general applications will be briefly reviewed.

U2 - 10.1016/B978-0-12-385118-5.00002-5

DO - 10.1016/B978-0-12-385118-5.00002-5

M3 - Article

C2 - 21943890

VL - 500

SP - 15

EP - 35

JO - Methods in Enzymology

JF - Methods in Enzymology

ER -

Mass spectrometry in systems biology an introduction

Abstract

Bibliographical note

Access to Document

Fingerprint

Cite this