Abstract
We report a case of acute myeloblastic leukaemia (AML), FAB type M2, with karyotype t(8;21)(q22;q22), who at the time of relapse showed marked eosinophilia of the bone marrow. Karyotype analysis showed the appearance of an additional clone t(8;21)(q22;q22),t(12;20)(q24;q11). To the best of our knowledge, marked eosinophilia has not been reported in association with this particular chromosomal translocation.
| Original language | English |
|---|---|
| Pages (from-to) | 181-2 |
| Number of pages | 2 |
| Journal | Leukemia and Lymphoma |
| Volume | 22 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - Jun 1996 |
Keywords
- Adult
- Antineoplastic Combined Chemotherapy Protocols
- Bone Marrow
- Chromosomes, Human, Pair 12
- Chromosomes, Human, Pair 20
- Chromosomes, Human, Pair 21
- Chromosomes, Human, Pair 8
- Cytarabine
- Daunorubicin
- Eosinophilia
- Etoposide
- Humans
- Idarubicin
- Leukemia, Myeloid, Acute
- Male
- Neoplasm Recurrence, Local
- Remission Induction
- Translocation, Genetic
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