Manipulation of the Renin Angiotensin System in Peripheral Arterial Disease

Simon Hobbs; Mark Thomas; Andrew Bradbury

doi:10.1016/j.ejvs.2004.08.003

Manipulation of the Renin Angiotensin System in Peripheral Arterial Disease

Simon Hobbs
, Mark Thomas
, Andrew Bradbury

Research output: Contribution to journal › Review article

13 Citations (Scopus)

Abstract

The Heart Outcomes Prevention Evaluation (HOPE) study has provided evidence for the use of ramipril for secondary cardiac prevention for patients with peripheral arterial disease. Despite this many vascular surgeons and general practitioners are reluctant to prescribe ACE inhibitors in a group of patients perceived to have a high incidence of renal artery stenosis. This review aims to review the pathophysiology of the renin-angiotensin system and make evidence based recommendations for commencing ACE inhibitors as part of a comprehensive delivery of best medical therapy to patients with peripheral arterial disease.

Original language	English
Pages (from-to)	573-582
Number of pages	10
Journal	European Journal of Vascular and Endovascular Surgery
Volume	28
DOIs	https://doi.org/10.1016/j.ejvs.2004.08.003
Publication status	Published - 1 Jan 2004

Access to Document

10.1016/j.ejvs.2004.08.003

Cite this

@article{9957fb4fc33e4ee786751de50e6f67aa,

title = "Manipulation of the Renin Angiotensin System in Peripheral Arterial Disease",

abstract = "The Heart Outcomes Prevention Evaluation (HOPE) study has provided evidence for the use of ramipril for secondary cardiac prevention for patients with peripheral arterial disease. Despite this many vascular surgeons and general practitioners are reluctant to prescribe ACE inhibitors in a group of patients perceived to have a high incidence of renal artery stenosis. This review aims to review the pathophysiology of the renin-angiotensin system and make evidence based recommendations for commencing ACE inhibitors as part of a comprehensive delivery of best medical therapy to patients with peripheral arterial disease.",

author = "Simon Hobbs and Mark Thomas and Andrew Bradbury",

year = "2004",

month = jan,

day = "1",

doi = "10.1016/j.ejvs.2004.08.003",

language = "English",

volume = "28",

pages = "573--582",

journal = "European Journal of Vascular and Endovascular Surgery",

publisher = "Elsevier",

}

TY - JOUR

T1 - Manipulation of the Renin Angiotensin System in Peripheral Arterial Disease

AU - Hobbs, Simon

AU - Thomas, Mark

AU - Bradbury, Andrew

PY - 2004/1/1

Y1 - 2004/1/1

N2 - The Heart Outcomes Prevention Evaluation (HOPE) study has provided evidence for the use of ramipril for secondary cardiac prevention for patients with peripheral arterial disease. Despite this many vascular surgeons and general practitioners are reluctant to prescribe ACE inhibitors in a group of patients perceived to have a high incidence of renal artery stenosis. This review aims to review the pathophysiology of the renin-angiotensin system and make evidence based recommendations for commencing ACE inhibitors as part of a comprehensive delivery of best medical therapy to patients with peripheral arterial disease.

AB - The Heart Outcomes Prevention Evaluation (HOPE) study has provided evidence for the use of ramipril for secondary cardiac prevention for patients with peripheral arterial disease. Despite this many vascular surgeons and general practitioners are reluctant to prescribe ACE inhibitors in a group of patients perceived to have a high incidence of renal artery stenosis. This review aims to review the pathophysiology of the renin-angiotensin system and make evidence based recommendations for commencing ACE inhibitors as part of a comprehensive delivery of best medical therapy to patients with peripheral arterial disease.

UR - https://www.scopus.com/pages/publications/7744235528

U2 - 10.1016/j.ejvs.2004.08.003

DO - 10.1016/j.ejvs.2004.08.003

M3 - Review article

C2 - 15531190

VL - 28

SP - 573

EP - 582

JO - European Journal of Vascular and Endovascular Surgery

JF - European Journal of Vascular and Endovascular Surgery

ER -

Manipulation of the Renin Angiotensin System in Peripheral Arterial Disease

Abstract

Access to Document

Fingerprint

Cite this