Managing patients receiving sorafenib for advanced hepatocellular carcinoma: a case study.

Diana Hull, Ceri Armstrong

Research output: Contribution to journalArticle

Abstract

Despite improvements in cytotoxic chemotherapy agents over the last 50 years, the outlook for patients with many of the most common solid tumours has remained poor. However, in recent years a number of targeted therapies have been licensed in the European Union for use in these cancer types. One such therapy, a tyrosine kinase inhibitor (sorafenib) is now used to treat patients with advanced hepatocellular carcinoma (HCC) and metastatic renal cell carcinoma. This article will explore the role of the oncology nurse in managing patients receiving sorafenib for advanced HCC. A brief overview of sorafenib as a current treatment approved for advanced HCC in the palliative setting is presented. This is followed by a case study-based discussion with particular reference to some of the key care coordination challenges facing the oncology nurse. The management of treatment-related adverse events and the importance of using a multidisciplinary team approach is also reviewed.
Original languageEnglish
Pages (from-to)249-54
Number of pages6
JournalInternational Journal of Palliative Nursing
Volume16
Issue number5
Publication statusPublished - 1 May 2010

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