Management of advanced nodal disease in patients treated with primary chemoradiotherapy

Hisham Mehanna; Wai Lup Wong; Janet Dunn

doi:10.1097/CCO.0000000000000283

Management of advanced nodal disease in patients treated with primary chemoradiotherapy

Hisham Mehanna, Wai Lup Wong, Janet Dunn

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Abstract

PURPOSE OF REVIEW: The management of advanced nodal disease in patients treated with chemoradiotherapy has been a controversial topic for many years. New data have recently been reported, including the results of a multicentre randomized trial making this review timely.

RECENT FINDINGS: The PET-NECK trial showed that PET-computer tomography (CT) surveillance is as effective as planned neck dissection in terms of overall survival, but results in much fewer neck dissections, less complications and is more cost effective. Cost-effectiveness data from a single centre study demonstrated that strategies that include PET-CT were more effective than CT-alone-guided strategies.

SUMMARY: There is now level 1 evidence to support image-guided surveillance strategies as the standard of care for advanced nodal disease in patients treated with primary chemoradiotherapy.

Original language	English
Pages (from-to)	201-4
Number of pages	4
Journal	Current opinion in oncology
Volume	28
Issue number	3
DOIs	https://doi.org/10.1097/CCO.0000000000000283
Publication status	Published - May 2016

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Mehanna_et_al_Management_advanced_nodal_disease_Current_Opinion_Oncology_Accepted
Article is not the final published version. Final Version of Record published as above. Checked April 2016
Accepted author manuscript, 396 KBLicence: None: All rights reserved

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title = "Management of advanced nodal disease in patients treated with primary chemoradiotherapy",

abstract = "PURPOSE OF REVIEW: The management of advanced nodal disease in patients treated with chemoradiotherapy has been a controversial topic for many years. New data have recently been reported, including the results of a multicentre randomized trial making this review timely.RECENT FINDINGS: The PET-NECK trial showed that PET-computer tomography (CT) surveillance is as effective as planned neck dissection in terms of overall survival, but results in much fewer neck dissections, less complications and is more cost effective. Cost-effectiveness data from a single centre study demonstrated that strategies that include PET-CT were more effective than CT-alone-guided strategies.SUMMARY: There is now level 1 evidence to support image-guided surveillance strategies as the standard of care for advanced nodal disease in patients treated with primary chemoradiotherapy.",

author = "Hisham Mehanna and Wong, {Wai Lup} and Janet Dunn",

year = "2016",

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doi = "10.1097/CCO.0000000000000283",

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AU - Wong, Wai Lup

AU - Dunn, Janet

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N2 - PURPOSE OF REVIEW: The management of advanced nodal disease in patients treated with chemoradiotherapy has been a controversial topic for many years. New data have recently been reported, including the results of a multicentre randomized trial making this review timely.RECENT FINDINGS: The PET-NECK trial showed that PET-computer tomography (CT) surveillance is as effective as planned neck dissection in terms of overall survival, but results in much fewer neck dissections, less complications and is more cost effective. Cost-effectiveness data from a single centre study demonstrated that strategies that include PET-CT were more effective than CT-alone-guided strategies.SUMMARY: There is now level 1 evidence to support image-guided surveillance strategies as the standard of care for advanced nodal disease in patients treated with primary chemoradiotherapy.

AB - PURPOSE OF REVIEW: The management of advanced nodal disease in patients treated with chemoradiotherapy has been a controversial topic for many years. New data have recently been reported, including the results of a multicentre randomized trial making this review timely.RECENT FINDINGS: The PET-NECK trial showed that PET-computer tomography (CT) surveillance is as effective as planned neck dissection in terms of overall survival, but results in much fewer neck dissections, less complications and is more cost effective. Cost-effectiveness data from a single centre study demonstrated that strategies that include PET-CT were more effective than CT-alone-guided strategies.SUMMARY: There is now level 1 evidence to support image-guided surveillance strategies as the standard of care for advanced nodal disease in patients treated with primary chemoradiotherapy.

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VL - 28

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JO - Current opinion in oncology

JF - Current opinion in oncology

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ER -

Management of advanced nodal disease in patients treated with primary chemoradiotherapy

Abstract

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