Making sense of leadership in urban and regional development. Regional Studies. This editorial paves the way for the articles addressing several contemporary sub-national leadership experiences in England, Australia, Finland, China, the Netherlands, Norway, Estonia, Denmark and Sweden. It introduces place leadership as a mode of reflexive agency in urban and regional development, and discusses the value as well as the difficulties and limitations of studying it. Place leadership has the potential to provide an additional ‘agential’ lens through which issues and relationships of structure and agency can be explored in urban and regional development.