Abstract
By shrinking the macrocycle in the CuAAC active template reaction not only is it demonstrated to be possible to use smaller macrocycles, but, surprisingly, that smaller macrocycles lead to higher yields of rotaxane product (see scheme). The synthesis of "small" functionalized [2]rotaxanes showcases this as a method for the production of materials with potential applications in molecular electronics, drug delivery, sensing, and enantioselective catalysis.
| Original language | English |
|---|---|
| Pages (from-to) | 4151-4155 |
| Number of pages | 5 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 50 |
| Issue number | 18 |
| DOIs | |
| Publication status | Published - 26 Apr 2011 |
Keywords
- click chemistry
- macrocycles
- rotaxanes
- self-assembly
- template synthesis
ASJC Scopus subject areas
- Catalysis
- General Chemistry