Loss of CD151/Tspan24 from the complex with integrin α3β1 in invasive front of the tumour is a negative predictor of disease-free survival in oral squamous cell carcinoma

H M Romanska; P Potemski; S I Collins; H Williams; S Parmar; F Berditchevski

doi:10.1016/j.oraloncology.2012.09.013

Loss of CD151/Tspan24 from the complex with integrin α3β1 in invasive front of the tumour is a negative predictor of disease-free survival in oral squamous cell carcinoma

H M Romanska, P Potemski, S I Collins, H Williams, S Parmar, F Berditchevski

Cancer and Genomic Sciences

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The study aimed to assess the role of CD151-integrin α3β1 (INGA3) complex as a potential prognostic indicator in OSCC and to examine whether mapping of its expression in the invasive front separately from that in the rest of the tumour would have an impact on the predictive value of the results. CD151/INGA3 profiles were compared with that of EGFR.

Original language	English
Pages (from-to)	224-9
Number of pages	6
Journal	Oral Oncology
Volume	49
Issue number	3
DOIs	https://doi.org/10.1016/j.oraloncology.2012.09.013
Publication status	Published - Mar 2013

Bibliographical note

Keywords

Adolescent
Adult
Aged
Aged, 80 and over
Antigens, CD151
Carcinoma, Squamous Cell
Cohort Studies
Disease-Free Survival
Epithelium
Female
Follow-Up Studies
Humans
Immunohistochemistry
Integrin alpha3
Integrin alpha3beta1
Lymph Nodes
Male
Middle Aged
Mouth Mucosa
Mouth Neoplasms
Neoplasm Grading
Neoplasm Invasiveness
Neoplasm Staging
Predictive Value of Tests
Prognosis
Receptor, Epidermal Growth Factor
Tumor Markers, Biological
Young Adult

Access to Document

10.1016/j.oraloncology.2012.09.013

Cite this

@article{0ba2b1f1f6b44dbeaa67e9c9051f1f43,

title = "Loss of CD151/Tspan24 from the complex with integrin α3β1 in invasive front of the tumour is a negative predictor of disease-free survival in oral squamous cell carcinoma",

abstract = "The study aimed to assess the role of CD151-integrin α3β1 (INGA3) complex as a potential prognostic indicator in OSCC and to examine whether mapping of its expression in the invasive front separately from that in the rest of the tumour would have an impact on the predictive value of the results. CD151/INGA3 profiles were compared with that of EGFR.",

keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Antigens, CD151, Carcinoma, Squamous Cell, Cohort Studies, Disease-Free Survival, Epithelium, Female, Follow-Up Studies, Humans, Immunohistochemistry, Integrin alpha3, Integrin alpha3beta1, Lymph Nodes, Male, Middle Aged, Mouth Mucosa, Mouth Neoplasms, Neoplasm Grading, Neoplasm Invasiveness, Neoplasm Staging, Predictive Value of Tests, Prognosis, Receptor, Epidermal Growth Factor, Tumor Markers, Biological, Young Adult",

author = "Romanska, {H M} and P Potemski and Collins, {S I} and H Williams and S Parmar and F Berditchevski",

year = "2013",

month = mar,

doi = "10.1016/j.oraloncology.2012.09.013",

language = "English",

volume = "49",

pages = "224--9",

journal = "Oral Oncology",

issn = "1368-8375",

publisher = "Elsevier",

number = "3",

}

TY - JOUR

T1 - Loss of CD151/Tspan24 from the complex with integrin α3β1 in invasive front of the tumour is a negative predictor of disease-free survival in oral squamous cell carcinoma

AU - Romanska, H M

AU - Potemski, P

AU - Collins, S I

AU - Williams, H

AU - Parmar, S

AU - Berditchevski, F

PY - 2013/3

Y1 - 2013/3

N2 - The study aimed to assess the role of CD151-integrin α3β1 (INGA3) complex as a potential prognostic indicator in OSCC and to examine whether mapping of its expression in the invasive front separately from that in the rest of the tumour would have an impact on the predictive value of the results. CD151/INGA3 profiles were compared with that of EGFR.

AB - The study aimed to assess the role of CD151-integrin α3β1 (INGA3) complex as a potential prognostic indicator in OSCC and to examine whether mapping of its expression in the invasive front separately from that in the rest of the tumour would have an impact on the predictive value of the results. CD151/INGA3 profiles were compared with that of EGFR.

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Antigens, CD151

KW - Carcinoma, Squamous Cell

KW - Cohort Studies

KW - Disease-Free Survival

KW - Epithelium

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Immunohistochemistry

KW - Integrin alpha3

KW - Integrin alpha3beta1

KW - Lymph Nodes

KW - Male

KW - Middle Aged

KW - Mouth Mucosa

KW - Mouth Neoplasms

KW - Neoplasm Grading

KW - Neoplasm Invasiveness

KW - Neoplasm Staging

KW - Predictive Value of Tests

KW - Prognosis

KW - Receptor, Epidermal Growth Factor

KW - Tumor Markers, Biological

KW - Young Adult

U2 - 10.1016/j.oraloncology.2012.09.013

DO - 10.1016/j.oraloncology.2012.09.013

M3 - Article

C2 - 23099281

SN - 1368-8375

VL - 49

SP - 224

EP - 229

JO - Oral Oncology

JF - Oral Oncology

IS - 3

ER -

Loss of CD151/Tspan24 from the complex with integrin α3β1 in invasive front of the tumour is a negative predictor of disease-free survival in oral squamous cell carcinoma

Abstract

Bibliographical note

Keywords

Access to Document

Fingerprint

Cite this