TY - JOUR
T1 - Localized bowel vasculitis
T2 - postoperative cyclophosphamide or not?
AU - Raza, Karim
AU - Buckley, Christopher
AU - Exley, Andrew
AU - Carruthers, David
AU - Buckley, Christopher
AU - Hammond, LA
AU - Bacon, Paul
PY - 1999/1
Y1 - 1999/1
N2 - We describe 2 patients with necrotizing vasculitis localized to the bowel, who were treated by excision of the involved tissue. Postoperatively, there was no evidence of active vasculitis, and both patients remain in remission on followup, without the use of immunosuppressive treatment. Evidence that an abnormal local microenvironment is necessary to sustain chronic inflammation may explain why surgical excision can be an important tool in the treatment of vasculitis.
AB - We describe 2 patients with necrotizing vasculitis localized to the bowel, who were treated by excision of the involved tissue. Postoperatively, there was no evidence of active vasculitis, and both patients remain in remission on followup, without the use of immunosuppressive treatment. Evidence that an abnormal local microenvironment is necessary to sustain chronic inflammation may explain why surgical excision can be an important tool in the treatment of vasculitis.
U2 - 10.1002/1529-0131(199901)42:1<182::AID-ANR22>3.0.CO;2-4
DO - 10.1002/1529-0131(199901)42:1<182::AID-ANR22>3.0.CO;2-4
M3 - Article
SN - 0004-3591
VL - 42
SP - 182
EP - 185
JO - Arthritis & Rheumatism
JF - Arthritis & Rheumatism
IS - 1
ER -