Localized bowel vasculitis: postoperative cyclophosphamide or not?

Karim Raza, Christopher Buckley, Andrew Exley, David Carruthers, Christopher Buckley, LA Hammond, Paul Bacon

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We describe 2 patients with necrotizing vasculitis localized to the bowel, who were treated by excision of the involved tissue. Postoperatively, there was no evidence of active vasculitis, and both patients remain in remission on followup, without the use of immunosuppressive treatment. Evidence that an abnormal local microenvironment is necessary to sustain chronic inflammation may explain why surgical excision can be an important tool in the treatment of vasculitis.
Original languageEnglish
Pages (from-to)182-185
JournalArthritis & Rheumatism
Issue number1
Early online date22 May 2001
Publication statusPublished - Jan 1999


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