Lip hypertrophy secondary to cyclosporin treatment

JC Cansick, Sally-Anne Hulton

Research output: Contribution to journalArticle

5 Citations (Scopus)


Gingival hypertrophy is a well-documented side effect of cyclosporin therapy, but severe lip enlargement is less frequently recognised. This can lead to poor body image, low self-esteem and non-compliance, especially in the older childhood and adolescent age groups. We describe two paediatric renal transplant recipients who had marked lip hypertrophy as a consequence of cyclosporin (Neoral) treatment. On changing the immunosuppression to tacrolimus (Prograf), this resolved. We recommend that a change in immunosuppressant therapy be considered in children with significant changes to facial appearance.
Original languageEnglish
Pages (from-to)710-711
Number of pages2
JournalPediatric Nephrology
Publication statusPublished - 1 Jan 2003


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