Abstract
An efficient, mild and operationally simple Ni-catalysed sp 3-carbon-to-sp3-carbon homocoupling of unactivated alkyl bromides has been developed and utilised in the active metal template synthesis of an alkyl chain axle [2]rotaxane. The key to the transformation is the use of tridentate nitrogen-donor-atom (terpy or pybox derived) ligands which inhibit competing β-hydride elimination of alkyl-Ni intermediates.
Original language | English |
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Pages (from-to) | 383-386 |
Number of pages | 4 |
Journal | Chemical Science |
Volume | 1 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Sept 2010 |
ASJC Scopus subject areas
- General Chemistry