Latent structure of irritable bowel syndrome symptom severity

Fabian Jasper, Boris Egloff, Andrea Roalfe, Michael Witthöft

    Research output: Contribution to journalArticlepeer-review

    8 Citations (Scopus)


    AIM: To investigate the latent structure of an irritable bowel syndrome (IBS) symptom severity scale in a population of healthy adults.

    METHODS: The Birmingham IBS symptom questionnaire which consists of three symptom specific scales (diarrhea, constipation, pain) was evaluated by means of structural equation modeling. We compared the original 3-factor solution to a general factor model and a bifactor solution in a large internet sample of college students (n = 875). Statistical comparisons of competing models were conducted by means of χ (2) difference tests. Regarding the evaluation of model fit, we examined the comparative fit index (CFI) and the Root Mean Square Error of Approximation (RMSEA).

    RESULTS: Results clearly favored a bifactor model of IBS symptom severity (CFI = 0.99, RMSEA = 0.05) which consisted of a strong general IBS somatization factor and three symptom specific factors (diarrhea, constipation, pain) based on the subscales of the Birmingham IBS symptom questionnaire. The fit indices of the competing one factor model (CFI = 0.85, RMSEA = 0.17) and three factor model (CFI = 0.97, RMSEA = 0.08) were clearly inferior. χ (2) difference tests showed that the differences between the models were indeed significant in favor of the bifactor model (P < 0.001). Correlations of the four latent factors with measures of pain sensitivity, somatoform dissociation, fatigue severity, and demographic variables support the validity of our bifactor model of IBS specific symptom severity.

    CONCLUSION: The findings suggest that IBS symptom severity might best be understood as a continuous and multidimensional construct which can be reliably and validly assessed with the B-IBS.

    Original languageEnglish
    Pages (from-to)292-300
    Number of pages9
    JournalWorld Journal of Gastroenterology
    Issue number1
    Publication statusPublished - 7 Jan 2015


    • Abdominal Pain
    • Adolescent
    • Adult
    • Chi-Square Distribution
    • Constipation
    • Diarrhea
    • Factor Analysis, Statistical
    • Fatigue
    • Female
    • Healthy Volunteers
    • Humans
    • Irritable Bowel Syndrome
    • Male
    • Models, Statistical
    • Pain Measurement
    • Predictive Value of Tests
    • Questionnaires
    • Reproducibility of Results
    • Severity of Illness Index
    • Young Adult


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