Abstract
The synthesis and kinetic resolution of quaternary oxindoles through copper catalysed azide-alkyne cycloadditions is presented. Selectivity factors (s) up to 22.1 ± 0.5 are reported. Enantioenriched alkynes and triazoles were obtained in ≥80% enantiomeric excess (e.e.).
Original language | English |
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Pages (from-to) | 17217-17220 |
Journal | Chemical Communications |
Volume | 51 |
Issue number | 97 |
Early online date | 27 Aug 2015 |
DOIs | |
Publication status | Published - 18 Dec 2015 |